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bv2 microglia cells  (Procell Inc)

 
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    Procell Inc bv2 microglia cells
    Bv2 Microglia Cells, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bv2+microglia+cells/bv2+cells/pm42138476-87-5-11
    Average 86 stars, based on 1 article reviews
    bv2 microglia cells - by Bioz Stars, 2026-10
    86/100 stars

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    Cell Culture:

    Article Title: Resveratrol alleviates depressive-like behavior via the activation of SIRT1/NF-κB signaling pathway in microglia
    Article Snippet: The fluorescence was then visualized and captured under a fluorescence microscope (Olympus, Tokyo, Japan). .. BV2 microglia cells were purchased from Procell (Wuhan, China), and cultured in MEM (CELL RESEARCH, Shanghai, China) with 5% CO 2 at 37 °C and supplemented with 10% fetal bovine serum (FBS) and 100 U/mL penicillin/streptomycin. ..

    Article Title: Ethnic Medicine Bauhinia Brachycarpa Benth Regulates Microglia-Neuron Interaction In Neuropathic Pain Via P2X4R-BDNF-TrkB Pathway
    Article Snippet: .. BV2 microglia cells were obtained from Procell Life Science and Technology Co. Ltd. (Wuhan, China) and cultured in high-glucose DMEM supplemented with 10% FBS in a CO2 incubator (5% CO2, 37°C). ..

    Article Title: Resveratrol alleviates depressive-like behavior via the activation of SIRT1/NF-κB signaling pathway in microglia.
    Article Snippet: .. Cell culture BV2 microglia cells were purchased from procell (Wuhan, China), and cultured in mEm (CELL RESEaRCH, Shanghai, China) with 5% Co2 at 37 °C and supplemented with 10% fetal bovine serum (FBS) and 100 u/mL penicillin/streptomycin. to explore the effect of resveratrol on microglia activity, BV2 cells were randomly divided into Control group, LpS group (LpS, 25ug/ml), LpS + resveratrol treated group (10 μm, 20 μm, 30 μm, 50 μm). ..

    Article Title: Ultrasound-guided HUC-MSCs transplantation alleviates neuropathic pain in CCI rats: a mechanistic study based on microglia/macrophage polarization and the NLRP3 inflammasome.
    Article Snippet: This study investigates the therapeutic effects of ultrasound-guided transplantation of human umbilical cord mesenchymal stem cells (HUC-MSCs) on nerve injury and neuronal recovery in chronic constriction injury (CCI) rats.. Behavioral analysis showed that HUC-MSCs treatment significantly improved Paw Mechanical Withdrawal Threshold (PMWT) and Thermal Paw Withdrawal Latency (TWL), with faster recovery in the HUC-MSCs groups.. Histological analysis revealed enhanced repair and regeneration, reduced inflammation, and improved results in the dual-treatment group (CCI + U2).

    Article Title: Tetramethylpyrazine-caffeic Acid Hybrid CT-011 Exerts Dopaminergic Neuroprotection Through Inhibiting Microglia-mediated Neuroinflammation.
    Article Snippet: Parkinson’s disease (PD) is the second most prevalent neurological disorder without a clear etiology and specific cure.. Microglia-mediated neuroinflammation plays a pivotal role in the pathogenesis and progression of PD, which is influenced by various factors and involves multiple signaling pathways.. CT-011, synthesized by combining nitrone-tetramethyl pyrazine (TMP) and caffeic acid through an ester bond, has shown neuroprotection against ischemic stroke and glutamate-induced neuronal damage in animal models.

    Activity Assay:

    Article Title: Resveratrol alleviates depressive-like behavior via the activation of SIRT1/NF-κB signaling pathway in microglia.
    Article Snippet: .. Cell culture BV2 microglia cells were purchased from procell (Wuhan, China), and cultured in mEm (CELL RESEaRCH, Shanghai, China) with 5% Co2 at 37 °C and supplemented with 10% fetal bovine serum (FBS) and 100 u/mL penicillin/streptomycin. to explore the effect of resveratrol on microglia activity, BV2 cells were randomly divided into Control group, LpS group (LpS, 25ug/ml), LpS + resveratrol treated group (10 μm, 20 μm, 30 μm, 50 μm). ..

    Control:

    Article Title: Resveratrol alleviates depressive-like behavior via the activation of SIRT1/NF-κB signaling pathway in microglia.
    Article Snippet: .. Cell culture BV2 microglia cells were purchased from procell (Wuhan, China), and cultured in mEm (CELL RESEaRCH, Shanghai, China) with 5% Co2 at 37 °C and supplemented with 10% fetal bovine serum (FBS) and 100 u/mL penicillin/streptomycin. to explore the effect of resveratrol on microglia activity, BV2 cells were randomly divided into Control group, LpS group (LpS, 25ug/ml), LpS + resveratrol treated group (10 μm, 20 μm, 30 μm, 50 μm). ..



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    Image Search Results


    Regulatory effects of miR-511-3p on the AKT3/USP8 in BV2 cells. (A–C) . Relative expression of miR-511-3p/AKT3/USP8 in BV2 cell model. (D) . miR-511-3p mimic promoted miR-511-3p expression. (E) . pcDNA3.1-AKT3 promoted AKT3 expression, but miR-511-3p mimic inhibited AKT3 expression, while this inhibition was rescued by pcDNA3.1-AKT3. (F) . pcDNA3.1-AKT3 inhibited USP8 expression, but miR-511-3p mimic promoted USP8 expression, while this promotion was rescued by pcDNA3.1-AKT3. ** P < 0.01, *** P < 0.001, compared to mimic NC; ## P < 0.01, compared to pcDNA3.1; & P < 0.05, &&& P < 0.001, compared to miR-511-3p mimic.

    Journal: Frontiers in Immunology

    Article Title: miR-511-3p dysregulation-mediated AKT3/USP8 signaling imbalance: a molecular bridge between neuroinflammation and PSCI

    doi: 10.3389/fimmu.2026.1766326

    Figure Lengend Snippet: Regulatory effects of miR-511-3p on the AKT3/USP8 in BV2 cells. (A–C) . Relative expression of miR-511-3p/AKT3/USP8 in BV2 cell model. (D) . miR-511-3p mimic promoted miR-511-3p expression. (E) . pcDNA3.1-AKT3 promoted AKT3 expression, but miR-511-3p mimic inhibited AKT3 expression, while this inhibition was rescued by pcDNA3.1-AKT3. (F) . pcDNA3.1-AKT3 inhibited USP8 expression, but miR-511-3p mimic promoted USP8 expression, while this promotion was rescued by pcDNA3.1-AKT3. ** P < 0.01, *** P < 0.001, compared to mimic NC; ## P < 0.01, compared to pcDNA3.1; & P < 0.05, &&& P < 0.001, compared to miR-511-3p mimic.

    Article Snippet: The mouse microglia cell line BV2 cells (Procell, China, CL-0697) were resuscitated, seeded in six-well plates, added with DMEM containing 10% fetal bovine serum (FBS).

    Techniques: Expressing, Inhibition

    miR-511-3p inhibited inflammation by targeting AKT3/USP8 in the cell model. (A) The expression level of IL-1β was regulatory by miR-511-3p/AKT3/USP8. (B) The expression level of IL-6 was regulatory by miR-511-3p/AKT3/USP8. (C) The expression level of TNF-α was regulatory by miR-511-3p/AKT3/USP8. *** P < 0.001, compared to BV2; ## P < 0.01, ### P < 0.001, compared to BV2+OGD/R; & P < 0.05, && P < 0.01, &&& P < 0.001, compared to BV2+OGD/R+miR-511-3p mimic.

    Journal: Frontiers in Immunology

    Article Title: miR-511-3p dysregulation-mediated AKT3/USP8 signaling imbalance: a molecular bridge between neuroinflammation and PSCI

    doi: 10.3389/fimmu.2026.1766326

    Figure Lengend Snippet: miR-511-3p inhibited inflammation by targeting AKT3/USP8 in the cell model. (A) The expression level of IL-1β was regulatory by miR-511-3p/AKT3/USP8. (B) The expression level of IL-6 was regulatory by miR-511-3p/AKT3/USP8. (C) The expression level of TNF-α was regulatory by miR-511-3p/AKT3/USP8. *** P < 0.001, compared to BV2; ## P < 0.01, ### P < 0.001, compared to BV2+OGD/R; & P < 0.05, && P < 0.01, &&& P < 0.001, compared to BV2+OGD/R+miR-511-3p mimic.

    Article Snippet: The mouse microglia cell line BV2 cells (Procell, China, CL-0697) were resuscitated, seeded in six-well plates, added with DMEM containing 10% fetal bovine serum (FBS).

    Techniques: Expressing